Version 5.4
Homo sapiens Gene: MAPK15
Summary
InnateDB Gene IDBG-38945.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MAPK15
Gene Name mitogen-activated protein kinase 15
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000181085
Encoded Proteins
IDBP-38947
mitogen-activated protein kinase 15
IDBP-240223
mitogen-activated protein kinase 15
IDBP-240225
mitogen-activated protein kinase 15
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 8:143716259-143722458
Strand Forward strand
Band q24.3
Transcripts
ENST00000338033 ENSP00000337691
ENST00000395108 ENSP00000378540
ENST00000395107 ENSP00000378539
ENST00000484654
ENST00000475376
ENST00000461928
ENST00000533830
ENST00000528175
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 21 experimentally validated interaction(s) in this database.
Experimentally validated
Total 21 [view]
Protein-Protein 21 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004672 protein kinase activity
GO:0004707 MAP kinase activity
GO:0004713 protein tyrosine kinase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016772 transferase activity, transferring phosphorus-containing groups
GO:0017124 SH3 domain binding
Biological Process
GO:0000122 negative regulation of transcription from RNA polymerase II promoter
GO:0000165 MAPK cascade
GO:0001934 positive regulation of protein phosphorylation
GO:0006468 protein phosphorylation
GO:0008156 negative regulation of DNA replication
GO:0031398 positive regulation of protein ubiquitination
GO:0032355 response to estradiol
GO:0045732 positive regulation of protein catabolic process
GO:0046777 protein autophosphorylation
Cellular Component
GO:0005576 extracellular region
GO:0005622 intracellular
GO:0005634 nucleus
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000063704
View Gene Order
ENSBTAG00000019864
Not yet available
Cross-References
SwissProt Q8TD08
TrEMBL
UniProt Splice Variant
Entrez Gene 225689
UniGene Hs.493169
RefSeq NM_139021
HUGO HGNC:24667
OMIM
CCDS CCDS6409
HPRD
IMGT
EMBL AY065978 AY994058 BC028034
GenPept AAH28034 AAL40897 AAY44299
RNA Seq Atlas 225689

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca