Homo sapiens Gene: CPD
Summary
InnateDB Gene IDBG-38962.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CPD
Gene Name carboxypeptidase D
Synonyms GP180
Species Homo sapiens
Ensembl Gene ENSG00000108582
Encoded Proteins
carboxypeptidase D
carboxypeptidase D
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The metallocarboxypeptidase family of enzymes is divided into 2 subfamilies based on sequence similarities. The pancreatic carboxypeptidase-like and the regulatory B-type carboxypeptidase subfamilies. Carboxypeptidase D has been identified as a regulatory B-type carboxypeptidase. CPD is a homolog of duck gp180, a hepatitis B virus-binding protein. Transcript variants utilizing alternative polyadenylation signals exist for this gene. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 17:30378905-30469989
Strand Forward strand
Band q11.2
Transcripts
ENST00000225719 ENSP00000225719
ENST00000543464 ENSP00000444443
ENST00000580396
ENST00000581826
ENST00000584221 ENSP00000463763
ENST00000584051
ENST00000584050 ENSP00000466049
ENST00000583275
ENST00000588977
ENST00000579502 ENSP00000464255
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 10 experimentally validated interaction(s) in this database.
Experimentally validated
Total 10 [view]
Protein-Protein 10 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004181 metallocarboxypeptidase activity
GO:0004185 serine-type carboxypeptidase activity
GO:0008270 zinc ion binding
Biological Process
GO:0006508 proteolysis
Cellular Component
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Not yet available
Pathways
NETPATH
REACTOME
Golgi Associated Vesicle Biogenesis pathway
Clathrin derived vesicle budding pathway
trans-Golgi Network Vesicle Budding pathway
Membrane Trafficking pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL J3QRJ9
UniProt Splice Variant
Entrez Gene 1362
UniGene Hs.446079 Hs.606696 Hs.608790
RefSeq NM_001199775 NM_001304
HUGO HGNC:2301
OMIM 603102
CCDS CCDS11257 CCDS56025
HPRD 04375
IMGT
EMBL AC006050 AC090685
GenPept
RNA Seq Atlas 1362