Version 5.4
Homo sapiens Gene: HYAL4
Summary
InnateDB Gene IDBG-39012.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol HYAL4
Gene Name hyaluronoglucosaminidase 4
Synonyms CSHY
Species Homo sapiens
Ensembl Gene ENSG00000106302
Encoded Proteins
IDBP-39014
hyaluronoglucosaminidase 4
IDBP-481807
hyaluronoglucosaminidase 4
IDBP-480763
hyaluronoglucosaminidase 4
IDBP-473373
hyaluronoglucosaminidase 4
IDBP-482670
hyaluronoglucosaminidase 4
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a protein which is similar in structure to hyaluronidases. Hyaluronidases intracellularly degrade hyaluronan, one of the major glycosaminoglycans of the extracellular matrix. Hyaluronan is thought to be involved in cell proliferation, migration and differentiation. However, this protein has not yet been shown to have hyaluronidase activity. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 7:123828983-123877478
Strand Forward strand
Band q31.32
Transcripts
ENST00000223026 ENSP00000223026
ENST00000489978 ENSP00000419522
ENST00000488323 ENSP00000417872
ENST00000476325 ENSP00000417186
ENST00000483878 ENSP00000420264
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0004415 hyalurononglucosaminidase activity
Biological Process
GO:0005975 carbohydrate metabolic process
GO:0006027 glycosaminoglycan catabolic process
GO:0030207 chondroitin sulfate catabolic process
Cellular Component
GO:0009986 cell surface
GO:0016021 integral component of membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000029680
View Gene Order
ENSBTAG00000005548
Not yet available
Pathways
NETPATH
REACTOME
KEGG
hsa00531
Glycosaminoglycan degradation pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.28673
RefSeq NM_012269 XM_005250238
HUGO
OMIM
CCDS CCDS5789
HPRD 05148
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca