Version 5.4
Homo sapiens Gene: GOSR1
Summary
InnateDB Gene IDBG-39052.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol GOSR1
Gene Name golgi SNAP receptor complex member 1
Synonyms GOLIM2; GOS-28; GOS28; GOS28/P28; GS28; P28
Species Homo sapiens
Ensembl Gene ENSG00000108587
Encoded Proteins
IDBP-39054
golgi SNAP receptor complex member 1
IDBP-374610
golgi SNAP receptor complex member 1
IDBP-374613
golgi SNAP receptor complex member 1
IDBP-374615
golgi SNAP receptor complex member 1
IDBP-763790
IDBP-593173
golgi SNAP receptor complex member 1
IDBP-761240
IDBP-812518
golgi SNAP receptor complex member 1
IDBP-812521
golgi SNAP receptor complex member 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a trafficking membrane protein which transports proteins among the endoplasmic reticulum and the Golgi and between Golgi compartments. This protein is considered an essential component of the Golgi SNAP receptor (SNARE) complex. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 17:30477362-30527592
Strand Forward strand
Band q11.2
Transcripts
ENST00000225724 ENSP00000225724
ENST00000414833 ENSP00000414956
ENST00000451249 ENSP00000414441
ENST00000427274 ENSP00000396977
ENST00000467337 ENSP00000462638
ENST00000491489
ENST00000467635
ENST00000494918
ENST00000477885
ENST00000537788 ENSP00000438330
ENST00000579905
ENST00000581721 ENSP00000465115
ENST00000610619 ENSP00000479971
ENST00000620049 ENSP00000482171
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 22 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 22 [view]
Protein-Protein 21 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005484 SNAP receptor activity
Biological Process
GO:0006888 ER to Golgi vesicle-mediated transport
GO:0006891 intra-Golgi vesicle-mediated transport
GO:0015031 protein transport
GO:0042147 retrograde transport, endosome to Golgi
Cellular Component
GO:0000139 Golgi membrane
GO:0005794 Golgi apparatus
GO:0005801 cis-Golgi network
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0031201 SNARE complex
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000010392
View Gene Order
ENSBTAG00000004961
Not yet available
Pathways
NETPATH
REACTOME
KEGG
hsa04130
SNARE interactions in vesicular transport pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq NM_001007024 NM_001007025 NM_004871 XM_005258072
HUGO
OMIM
CCDS CCDS11258 CCDS45643 CCDS45644
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca