Version 5.4
Homo sapiens Gene: PDPR
Summary
InnateDB Gene IDBG-39706.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PDPR
Gene Name pyruvate dehydrogenase phosphatase regulatory subunit
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000090857
Encoded Proteins
IDBP-39708
pyruvate dehydrogenase phosphatase regulatory subunit
IDBP-233825
pyruvate dehydrogenase phosphatase regulatory subunit
IDBP-751465
IDBP-750477
IDBP-751949
IDBP-748919
IDBP-746580
IDBP-750213
IDBP-748403
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 16:70113626-70162537
Strand Forward strand
Band q22.1
Transcripts
ENST00000288050 ENSP00000288050
ENST00000398122 ENSP00000381190
ENST00000562100
ENST00000567046 ENSP00000456959
ENST00000569042 ENSP00000457636
ENST00000564563 ENSP00000456385
ENST00000563930 ENSP00000457961
ENST00000565186 ENSP00000455764
ENST00000568530 ENSP00000457916
ENST00000567896 ENSP00000457484
ENST00000561920
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004047 aminomethyltransferase activity
GO:0016491 oxidoreductase activity
Biological Process
GO:0006090 pyruvate metabolic process
GO:0006546 glycine catabolic process
GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate
GO:0032259 methylation
GO:0044237 cellular metabolic process
GO:0044281 small molecule metabolic process
GO:0055114 oxidation-reduction process
Cellular Component
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005759 mitochondrial matrix
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000033624
View Gene Order
ENSBTAG00000016471
Not yet available
Pathways
NETPATH
REACTOME
REACT_12528
Regulation of pyruvate dehydrogenase (PDH) complex pathway
REACT_2071
Pyruvate metabolism pathway
REACT_1046
Pyruvate metabolism and Citric Acid (TCA) cycle pathway
REACT_111083
The citric acid (TCA) cycle and respiratory electron transport pathway
REACT_111217
Metabolism pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.461183 Hs.651922
RefSeq NM_017990 XM_005256015 XM_005256016 XM_005256019 XM_006721226
HUGO
OMIM
CCDS CCDS45520
HPRD 17832
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca