Version 5.4
Homo sapiens Gene: RHOT1
Summary
InnateDB Gene IDBG-39866.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol RHOT1
Gene Name ras homolog family member T1
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000126858
Encoded Proteins
IDBP-39868
ras homolog gene family, member T1
IDBP-39870
ras homolog gene family, member T1
IDBP-39872
ras homolog gene family, member T1
IDBP-241032
ras homolog gene family, member T1
IDBP-593700
ras homolog gene family, member T1
IDBP-764772
IDBP-758652
IDBP-759133
IDBP-764060
IDBP-762794
IDBP-760114
IDBP-764047
IDBP-759003
IDBP-758223
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 17:32142454-32253374
Strand Forward strand
Band q11.2
Transcripts
ENST00000333942 ENSP00000334724
ENST00000358365 ENSP00000351132
ENST00000354266 ENSP00000346215
ENST00000394692 ENSP00000378184
ENST00000545287 ENSP00000439737
ENST00000584852 ENSP00000461992
ENST00000581031 ENSP00000464094
ENST00000582602 ENSP00000464851
ENST00000578205 ENSP00000462612
ENST00000581148 ENSP00000467272
ENST00000580392 ENSP00000463532
ENST00000583994 ENSP00000462698
ENST00000584692 ENSP00000464674
ENST00000581094 ENSP00000462669
ENST00000581567
ENST00000580976
ENST00000582586
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 12 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 12 [view]
Protein-Protein 12 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0003924 GTPase activity
GO:0005509 calcium ion binding
GO:0005515 protein binding
GO:0005525 GTP binding
Biological Process
GO:0006184 GTP catabolic process
GO:0007165 signal transduction
GO:0007264 small GTPase mediated signal transduction
GO:0015031 protein transport
GO:0019725 cellular homeostasis
GO:0047497 mitochondrion transport along microtubule
GO:0051056 regulation of small GTPase mediated signal transduction
GO:0097345 mitochondrial outer membrane permeabilization
Cellular Component
GO:0005622 intracellular
GO:0005739 mitochondrion
GO:0005741 mitochondrial outer membrane
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0031307 integral component of mitochondrial outer membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000017686
View Gene Order
ENSBTAG00000010001
Not yet available
Pathways
NETPATH
REACTOME
REACT_11051
Rho GTPase cycle pathway
REACT_11044
Signaling by Rho GTPases pathway
REACT_111102
Signal Transduction pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL H7BXZ6
UniProt Splice Variant
Entrez Gene 55288
UniGene Hs.655325 Hs.694015
RefSeq NM_001033567 NM_001288755 NM_001033566 NM_001033568 NM_001288754 NM_001288758 NM_018307 XM_005257996 XM_006721968
HUGO HGNC:21168
OMIM 613888
CCDS CCDS74031 CCDS32610 CCDS32611 CCDS32612 CCDS74030
HPRD 15247
IMGT
EMBL AC026620 AC116407 CH471147
GenPept EAW80251
RNA Seq Atlas 55288

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca