Version 5.4
Homo sapiens Gene: COG4
Summary
InnateDB Gene IDBG-40123.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol COG4
Gene Name component of oligomeric golgi complex 4
Synonyms CDG2J; COD1
Species Homo sapiens
Ensembl Gene ENSG00000103051
Encoded Proteins
IDBP-40127
component of oligomeric golgi complex 4
IDBP-243257
component of oligomeric golgi complex 4
IDBP-601942
component of oligomeric golgi complex 4
IDBP-752495
IDBP-587323
component of oligomeric golgi complex 4
IDBP-745939
IDBP-749963
IDBP-752976
IDBP-746507
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene is a component of an oligomeric protein complex involved in the structure and function of the Golgi apparatus. Defects in this gene may be a cause of congenital disorder of glycosylation type IIj. Two transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Aug 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 16:70480568-70523565
Strand Reverse strand
Band q22.1
Transcripts
ENST00000323786 ENSP00000315775
ENST00000393612 ENSP00000377236
ENST00000482252 ENSP00000432802
ENST00000530314
ENST00000526700
ENST00000534772 ENSP00000461912
ENST00000530160 ENSP00000434160
ENST00000524584 ENSP00000463732
ENST00000565715 ENSP00000455693
ENST00000564315
ENST00000564653 ENSP00000454573
ENST00000562200
ENST00000567244
ENST00000564415 ENSP00000456653
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 24 experimentally validated interaction(s) in this database.
Experimentally validated
Total 24 [view]
Protein-Protein 24 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0006890 retrograde vesicle-mediated transport, Golgi to ER
GO:0007030 Golgi organization
GO:0015031 protein transport
GO:0048213 Golgi vesicle prefusion complex stabilization
Cellular Component
GO:0000139 Golgi membrane
GO:0017119 Golgi transport complex
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000031753
View Gene Order
ENSBTAG00000012988
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.208680 Hs.615139
RefSeq NM_001195139 NM_015386 XM_006721174
HUGO
OMIM
CCDS CCDS10892 CCDS73909
HPRD 08444
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca