Version 5.4
Homo sapiens Gene: N4BP2L2
Summary
InnateDB Gene IDBG-401916.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol N4BP2L2
Gene Name NEDD4 binding protein 2-like 2
Synonyms 92M18.3; CG005; PFAAP5
Species Homo sapiens
Ensembl Gene ENSG00000244754
Encoded Proteins
IDBP-23168
NEDD4 binding protein 2-like 2
IDBP-23170
NEDD4 binding protein 2-like 2
IDBP-230778
NEDD4 binding protein 2-like 2
IDBP-364102
NEDD4 binding protein 2-like 2
IDBP-479917
NEDD4 binding protein 2-like 2
IDBP-480671
NEDD4 binding protein 2-like 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 13:32432417-32538885
Strand Reverse strand
Band q13.1
Transcripts
ENST00000357505 ENSP00000350104
ENST00000267068 ENSP00000267068
ENST00000399396 ENSP00000382328
ENST00000446957 ENSP00000394239
ENST00000504114 ENSP00000427477
ENST00000509076
ENST00000505213 ENSP00000423362
ENST00000473025
ENST00000503814
ENST00000511143
ENST00000475731
ENST00000512755
ENST00000483088
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 11 experimentally validated interaction(s) in this database.
Experimentally validated
Total 11 [view]
Protein-Protein 9 [view]
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0001106 RNA polymerase II transcription corepressor activity
GO:0003674 molecular_function
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016301 kinase activity
GO:0019899 enzyme binding
Biological Process
GO:0000122 negative regulation of transcription from RNA polymerase II promoter
GO:1902035 positive regulation of hematopoietic stem cell proliferation
GO:1902037 negative regulation of hematopoietic stem cell differentiation
Cellular Component
GO:0005737 cytoplasm
GO:0017053 transcriptional repressor complex
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000029655
View Gene Order
ENSBTAG00000023279
Not yet available
Cross-References
SwissProt
TrEMBL B4DPY1 Q6ZV26
UniProt Splice Variant
Entrez Gene 10443
UniGene Hs.507680
RefSeq NM_001278432 XM_005266223 NM_014887 NM_033111 XM_005266218 XM_005266219 XM_005266220 XM_005266221 XM_005266222 XM_005266224 XM_006719754
HUGO HGNC:26916
OMIM 615788
CCDS CCDS61307 CCDS45024 CCDS9346
HPRD 15119
IMGT
EMBL AK125067 AK298546 AL137247 AL353665
GenPept BAC86039 BAG60743
RNA Seq Atlas 102724071 10443

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca