Version 5.4
Homo sapiens Protein: N4BP2L2
Summary
InnateDB Protein IDBP-23170.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol N4BP2L2
Protein Name NEDD4 binding protein 2-like 2
Synonyms 92M18.3; CG005; PFAAP5;
Species Homo sapiens
Ensembl Protein ENSP00000267068
InnateDB Gene IDBG-401916 (N4BP2L2)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 11 experimentally validated interaction(s) in this database.
Experimentally validated
Total 11 [view]
Protein-Protein 9 [view]
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0001106 RNA polymerase II transcription corepressor activity
GO:0003674 molecular_function
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016301 kinase activity
GO:0019899 enzyme binding
Biological Process
GO:0000122 negative regulation of transcription from RNA polymerase II promoter
GO:1902035 positive regulation of hematopoietic stem cell proliferation
GO:1902037 negative regulation of hematopoietic stem cell differentiation
Cellular Component
GO:0005737 cytoplasm
GO:0017053 transcriptional repressor complex
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID
InterPro IPR010488 Zeta toxin domain
IPR027417 P-loop containing nucleoside triphosphate hydrolase
PFAM PF06414
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q92802
PhosphoSite PhosphoSite-Q92802
TrEMBL A0A024RDV2
UniProt Splice Variant
Entrez Gene 10443
UniGene Hs.507680
RefSeq NP_055702
HUGO HGNC:26916
OMIM 615788
CCDS CCDS9346
HPRD 15119
IMGT
EMBL AF530063 AL049783 AL353665 BC010643 BC131631 BP361938 BT007172 CH471075 U50532
GenPept AAC50875 AAH10643 AAI31632 AAP35836 AAQ09947 CAB42441 CAI11042 EAX08514 EAX08515

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca