Homo sapiens Gene: ADAMTS19
Summary
InnateDB Gene IDBG-40198.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ADAMTS19
Gene Name ADAM metallopeptidase with thrombospondin type 1 motif, 19
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000145808
Encoded Proteins
ADAM metallopeptidase with thrombospondin type 1 motif, 19
ADAM metallopeptidase with thrombospondin type 1 motif, 19
ADAM metallopeptidase with thrombospondin type 1 motif, 19
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motif) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The protein encoded by this gene has high sequence similarity to the protein encoded by ADAMTS16, another family member. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 5:129460265-129738683
Strand Forward strand
Band q23.3
Transcripts
ENST00000274487 ENSP00000274487
ENST00000505791 ENSP00000423537
ENST00000502709 ENSP00000422491
ENST00000509467
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0004222 metalloendopeptidase activity
GO:0008233 peptidase activity
GO:0008270 zinc ion binding
Biological Process
GO:0006508 proteolysis
Cellular Component
GO:0005578 proteinaceous extracellular matrix
GO:0031012 extracellular matrix
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Not yet available
Pathways
NETPATH
REACTOME
Post-translational protein modification pathway
O-linked glycosylation pathway
Metabolism of proteins pathway
O-glycosylation of TSR domain-containing proteins pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.23751 Hs.596004
RefSeq NM_133638
HUGO
OMIM
CCDS CCDS4146
HPRD 06334
IMGT
EMBL
GenPept
RNA Seq Atlas