Homo sapiens Protein: ADAMTS19
Summary
InnateDB Protein IDBP-40200.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ADAMTS19
Protein Name ADAM metallopeptidase with thrombospondin type 1 motif, 19
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000274487
InnateDB Gene IDBG-40198 (ADAMTS19)
Protein Structure
UniProt Annotation
Function
Subcellular Localization Secreted, extracellular space, extracellular matrix {ECO:0000250}.
Disease Associations
Tissue Specificity Expressed in fetal lung, but not in any adult tissues examined. Expression was detected in an osteosarcoma cDNA library.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0004222 metalloendopeptidase activity
GO:0008233 peptidase activity
GO:0008270 zinc ion binding
Biological Process
GO:0006508 proteolysis
Cellular Component
GO:0005578 proteinaceous extracellular matrix
GO:0031012 extracellular matrix
Protein Structure and Domains
PDB ID
InterPro IPR000884 Thrombospondin, type 1 repeat
IPR001590 Peptidase M12B, ADAM/reprolysin
IPR001818 Peptidase M10, metallopeptidase
IPR002870 Peptidase M12B, propeptide
IPR006586 ADAM, cysteine-rich
IPR010294 ADAM-TS Spacer 1
IPR010909 PLAC
IPR013273 Peptidase M12B, ADAM-TS
PFAM PF00090
PF01421
PF00413
PF01562
PF08516
PF05986
PF08686
PRINTS PR01857
PIRSF
SMART SM00209
SM00608
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8TE59
PhosphoSite PhosphoSite-Q8TE59
TrEMBL
UniProt Splice Variant
Entrez Gene 171019
UniGene Hs.596004
RefSeq NP_598377
HUGO HGNC:17111
OMIM 607513
CCDS CCDS4146
HPRD 06334
IMGT
EMBL AC008425 AC008528 AC008591 AC106781 AC129713 AJ311904
GenPept CAC84565