Homo sapiens Gene: STRC
Summary
InnateDB Gene IDBG-402174.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol STRC
Gene Name stereocilin
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000242866
Encoded Proteins
stereocilin
stereocilin
stereocilin
stereocilin
stereocilin
stereocilin
Protein Structure
Entrez Gene
Summary This gene encodes a protein that is associated with the hair bundle of the sensory hair cells in the inner ear. The hair bundle is composed of stiff microvilli called stereocilia and is involved with mechanoreception of sound waves. This gene is part of a tandem duplication on chromosome 15; the second copy is a pseudogene. Mutations in this gene cause autosomal recessive non-syndromic deafness. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 15:43599398-43618800
Strand Reverse strand
Band q15.3
Transcripts
ENST00000450892 ENSP00000401513
ENST00000428650 ENSP00000415991
ENST00000440125 ENSP00000394866
ENST00000455136 ENSP00000394755
ENST00000432436 ENSP00000407303
ENST00000448437
ENST00000471703
ENST00000485556
ENST00000460952
ENST00000493750
ENST00000483250
ENST00000470279
ENST00000541030 ENSP00000440413
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0050910 detection of mechanical stimulus involved in sensory perception of sound
GO:0060088 auditory receptor cell stereocilium organization
Cellular Component
GO:0009986 cell surface
GO:0032420 stereocilium
GO:0032426 stereocilium bundle tip
GO:0060091 kinocilium
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Cross-References
SwissProt Q7RTU9
TrEMBL E7EPM8 E9PBT5 F5GXA4 H7C2Q6
UniProt Splice Variant
Entrez Gene 161497
UniGene Hs.657395
RefSeq NM_153700 XM_006720407
HUGO HGNC:16035
OMIM 606440
CCDS CCDS10098
HPRD 08403
IMGT
EMBL AC011330 AC018512 BK000138
GenPept DAA00085
ImmGen STRC (murine)
RNA Seq Atlas 101930630 161497