Version 5.4
Homo sapiens Gene: SPACA3
Summary
InnateDB Gene IDBG-40382.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SPACA3
Gene Name sperm acrosome associated 3
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000141316
Encoded Proteins
IDBP-40384
sperm acrosome associated 3
IDBP-241183
sperm acrosome associated 3
IDBP-759019
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 17:32970376-32997877
Strand Forward strand
Band q11.2
Transcripts
ENST00000269053 ENSP00000269053
ENST00000394638 ENSP00000378134
ENST00000394637
ENST00000485015
ENST00000580599 ENSP00000463386
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003796 lysozyme activity
GO:0005515 protein binding
Biological Process
GO:0009253 peptidoglycan catabolic process
GO:0009615 response to virus
GO:0016998 cell wall macromolecule catabolic process
GO:0035036 sperm-egg recognition
GO:0042117 monocyte activation
GO:0043032 positive regulation of macrophage activation
GO:0050766 positive regulation of phagocytosis
GO:0050830 defense response to Gram-positive bacterium
Cellular Component
GO:0001669 acrosomal vesicle
GO:0002080 acrosomal membrane
GO:0005576 extracellular region
GO:0005764 lysosome
GO:0016021 integral component of membrane
GO:0030141 secretory granule
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000053184
View Gene Order
ENSBTAG00000000344
Not yet available
Cross-References
SwissProt Q8IXA5
TrEMBL
UniProt Splice Variant
Entrez Gene 124912
UniGene Hs.434112
RefSeq NM_173847
HUGO HGNC:16260
OMIM 612749
CCDS CCDS11275
HPRD 15420
IMGT
EMBL AF099029 AF216311 AY358653 BC100886 BC100887
GenPept AAI00887 AAI00888 AAK01478 AAP97222 AAQ89016
RNA Seq Atlas 124912

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca