Version 5.4
Homo sapiens Gene: PINX1
Summary
InnateDB Gene IDBG-404872.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PINX1
Gene Name PIN2/TERF1 interacting, telomerase inhibitor 1
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000254093
Encoded Proteins
IDBP-7142
PIN2/TERF1 interacting, telomerase inhibitor 1
IDBP-477187
PIN2/TERF1 interacting, telomerase inhibitor 1
IDBP-480088
PIN2/TERF1 interacting, telomerase inhibitor 1
IDBP-481064
PIN2/TERF1 interacting, telomerase inhibitor 1
IDBP-480099
PIN2/TERF1 interacting, telomerase inhibitor 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 8:10764963-10839884
Strand Reverse strand
Band p23.1
Transcripts
ENST00000314787 ENSP00000318966
ENST00000519088 ENSP00000428853
ENST00000524114 ENSP00000428728
ENST00000523559 ENSP00000428242
ENST00000524061 ENSP00000429346
ENST00000517607
ENST00000520018
ENST00000524026
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 33 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 33 [view]
Protein-Protein 32 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003676 nucleic acid binding
GO:0005515 protein binding
GO:0010521 telomerase inhibitor activity
GO:0070034 telomeric RNA binding
Biological Process
GO:0007004 telomere maintenance via telomerase
GO:0007080 mitotic metaphase plate congression
GO:0008285 negative regulation of cell proliferation
GO:0051972 regulation of telomerase activity
GO:0051974 negative regulation of telomerase activity
Cellular Component
GO:0000228 nuclear chromosome
GO:0000776 kinetochore
GO:0000777 condensed chromosome kinetochore
GO:0000781 chromosome, telomeric region
GO:0005730 nucleolus
GO:0005819 spindle
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000021958
View Gene Order
ENSBTAG00000000500
Not yet available
Pathways
NETPATH
REACTOME
KEGG
INOH
PID NCI
telomerasepathway
Regulation of Telomerase
Cross-References
SwissProt Q96BK5
TrEMBL F8WBT5
UniProt Splice Variant
Entrez Gene 54984
UniGene
RefSeq NM_001284356 NM_017884
HUGO HGNC:30046
OMIM 606505
CCDS CCDS64825 CCDS47801
HPRD 05934
IMGT
EMBL AC011008 AC105001 AF205718 AF418553 AJ344104 AK000572 AK313715 AY029161 AY238941 AY523566 BC015479 BC093762 CH471157
GenPept AAG18009 AAH15479 AAH93762 AAK31790 AAN31333 AAP37006 AAS19507 BAA91263 BAG36458 CAC51436 EAW65596
RNA Seq Atlas 54984

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca