Version 5.4
Homo sapiens Gene: PPIL3
Summary
InnateDB Gene IDBG-409196.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PPIL3
Gene Name peptidylprolyl isomerase (cyclophilin)-like 3
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000240344
Encoded Proteins
IDBP-78290
peptidylprolyl isomerase (cyclophilin)-like 3
IDBP-245973
peptidylprolyl isomerase (cyclophilin)-like 3
IDBP-293193
peptidylprolyl isomerase (cyclophilin)-like 3
IDBP-293192
peptidylprolyl isomerase (cyclophilin)-like 3
IDBP-293187
peptidylprolyl isomerase (cyclophilin)-like 3
IDBP-388278
peptidylprolyl isomerase (cyclophilin)-like 3
IDBP-388279
peptidylprolyl isomerase (cyclophilin)-like 3
IDBP-388280
peptidylprolyl isomerase (cyclophilin)-like 3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of the cyclophilin family. Cyclophilins catalyze the cis-trans isomerization of peptidylprolyl imide bonds in oligopeptides. They have been proposed to act either as catalysts or as molecular chaperones in protein-folding events. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:200870907-200889303
Strand Reverse strand
Band q33.1
Transcripts
ENST00000286175 ENSP00000286175
ENST00000392283 ENSP00000376107
ENST00000409264 ENSP00000386893
ENST00000409361 ENSP00000386235
ENST00000409449 ENSP00000387012
ENST00000415562 ENSP00000400726
ENST00000443398 ENSP00000391082
ENST00000457063 ENSP00000401196
ENST00000465823
ENST00000463866
ENST00000497263
ENST00000492074
ENST00000470442
ENST00000497501
ENST00000487879
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 20 experimentally validated interaction(s) in this database.
Experimentally validated
Total 20 [view]
Protein-Protein 20 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003755 peptidyl-prolyl cis-trans isomerase activity
GO:0005515 protein binding
Biological Process
GO:0000398 mRNA splicing, via spliceosome
GO:0000413 protein peptidyl-prolyl isomerization
GO:0006457 protein folding
Cellular Component
GO:0071013 catalytic step 2 spliceosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000026035
View Gene Order
ENSBTAG00000005416
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.599602
RefSeq NM_032472 NM_130906 XM_005246651 XM_005246652
HUGO
OMIM
CCDS CCDS2332 CCDS2333
HPRD 15163
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca