Version 5.4
Homo sapiens Gene: STK35
Summary
InnateDB Gene IDBG-40966.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol STK35
Gene Name serine/threonine kinase 35
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000125834
Encoded Proteins
IDBP-40968
serine/threonine kinase 35
IDBP-482238
serine/threonine kinase 35
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene is a kinase that is predominantly found in the nucleus. However, it can interact with PDLIM1/CLP-36 in the cytoplasm and localize to actin stress fibers. The encoded protein may be a regulator of actin stress fibers in nonmuscle cells. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 20:2101611-2177038
Strand Forward strand
Band p13
Transcripts
ENST00000381482 ENSP00000370891
ENST00000493263 ENSP00000426612
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
Experimentally validated
Total 7 [view]
Protein-Protein 7 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0004713 protein tyrosine kinase activity
GO:0005524 ATP binding
GO:0016772 transferase activity, transferring phosphorus-containing groups
Biological Process
GO:0006468 protein phosphorylation
Cellular Component
GO:0005730 nucleolus
GO:0005737 cytoplasm
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000037885
View Gene Order
ENSBTAG00000003561
Not yet available
Cross-References
SwissProt Q8TDR2
TrEMBL
UniProt Splice Variant
Entrez Gene 140901
UniGene Hs.100057
RefSeq NM_080836
HUGO HGNC:16254
OMIM 609370
CCDS CCDS13024
HPRD
IMGT
EMBL AF195026 AK314728 AL359916 BC017340 BC111573 BC140883 BC140884 GQ281297
GenPept AAH17340 AAI11574 AAI40884 AAI40885 AAL99353 ACU33925 BAG37270 CAI15590
RNA Seq Atlas 140901

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca