Homo sapiens Protein: STK35
Summary
InnateDB Protein IDBP-40968.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol STK35
Protein Name serine/threonine kinase 35
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000370891
InnateDB Gene IDBG-40966 (STK35)
Protein Structure
UniProt Annotation
Function
Subcellular Localization Nucleus. Nucleus, nucleolus. Cytoplasm. Note=When associated with PDLIM1, it is mostly found in cytoplasm, localized to actin stress fibers (PubMed:11973348). However, PubMed:19756140 detected STK35 only in the nucleus, and the presence of PDLIM1 had no influence on its location. {ECO:0000269PubMed:11973348}.
Disease Associations
Tissue Specificity Expressed in testis.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
Experimentally validated
Total 7 [view]
Protein-Protein 7 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0004713 protein tyrosine kinase activity
GO:0005524 ATP binding
GO:0016772 transferase activity, transferring phosphorus-containing groups
Biological Process
GO:0006468 protein phosphorylation
Cellular Component
GO:0005730 nucleolus
GO:0005737 cytoplasm
Protein Structure and Domains
PDB ID
InterPro IPR000719 Protein kinase domain
IPR001245 Serine-threonine/tyrosine-protein kinase catalytic domain
IPR002290 Serine/threonine/dual specificity protein kinase, catalytic domain
IPR011009 Protein kinase-like domain
IPR020635 Tyrosine-protein kinase, catalytic domain
PFAM PF00069
PF07714
PRINTS PR00109
PIRSF
SMART SM00220
SM00219
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8TDR2
PhosphoSite PhosphoSite-Q8TDR2
TrEMBL
UniProt Splice Variant
Entrez Gene 140901
UniGene Hs.100057
RefSeq NP_543026
HUGO HGNC:16254
OMIM 609370
CCDS CCDS13024
HPRD 11612
IMGT
EMBL AF195026 AK314728 AL359916 BC017340 BC111573 BC140883 BC140884 GQ281297
GenPept AAH17340 AAI11574 AAI40884 AAI40885 AAL99353 ACU33925 BAG37270 CAI15590