Version 5.4
Homo sapiens Gene: UNC45B
Summary
InnateDB Gene IDBG-41498.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol UNC45B
Gene Name unc-45 homolog B (C. elegans)
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000141161
Encoded Proteins
IDBP-41500
unc-45 homolog B (C. elegans)
IDBP-241314
unc-45 homolog B (C. elegans)
IDBP-759051
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary UNC45B plays a role in myoblast fusion and sarcomere organization (Price et al., 2002 [PubMed 12356907]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 17:35147817-35189345
Strand Forward strand
Band q12
Transcripts
ENST00000268876 ENSP00000268876
ENST00000394570 ENSP00000378071
ENST00000591048 ENSP00000468335
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
Experimentally validated
Total 7 [view]
Protein-Protein 7 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005488 binding
GO:0005515 protein binding
GO:0051879 Hsp90 protein binding
Biological Process
GO:0007517 muscle organ development
GO:0030154 cell differentiation
GO:0061077 chaperone-mediated protein folding
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000018845
View Gene Order
ENSBTAG00000002898
Not yet available
Cross-References
SwissProt Q8IWX7
TrEMBL
UniProt Splice Variant
Entrez Gene 146862
UniGene Hs.379636
RefSeq NM_001033576 NM_001267052 NM_173167
HUGO HGNC:14304
OMIM 611220
CCDS CCDS11292 CCDS45648
HPRD 10840
IMGT
EMBL AF539794 BC101062 BC101063
GenPept AAI01063 AAI01064 AAO13384
RNA Seq Atlas 146862

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca