Version 5.4
Homo sapiens Gene: SLITRK6
Summary
InnateDB Gene IDBG-41532.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SLITRK6
Gene Name SLIT and NTRK-like family, member 6
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000184564
Encoded Proteins
IDBP-228634
SLIT and NTRK-like family, member 6
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Members of the SLITRK family, such as SLITRK6, are integral membrane proteins with 2 N-terminal leucine-rich repeat (LRR) domains similar to those of SLIT proteins (see SLIT1; MIM 603742). Most SLITRKs, including SLITRK6, also have C-terminal regions that share homology with neurotrophin receptors (see NTRK1; MIM 191315). SLITRKs are expressed predominantly in neural tissues and have neurite-modulating activity (Aruga et al., 2003 [PubMed 14557068]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 13:85792790-85799488
Strand Reverse strand
Band q31.1
Transcripts
ENST00000400286 ENSP00000383143
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0001964 startle response
GO:0002088 lens development in camera-type eye
GO:0002093 auditory receptor cell morphogenesis
GO:0007409 axonogenesis
GO:0007416 synapse assembly
GO:0007601 visual perception
GO:0007605 sensory perception of sound
GO:0008344 adult locomotory behavior
GO:0021562 vestibulocochlear nerve development
GO:0031223 auditory behavior
GO:0035264 multicellular organism growth
GO:0042472 inner ear morphogenesis
GO:0043010 camera-type eye development
GO:0048812 neuron projection morphogenesis
GO:0060005 vestibular reflex
GO:0060007 linear vestibuloocular reflex
GO:0060384 innervation
GO:0090102 cochlea development
Cellular Component
GO:0005887 integral component of plasma membrane
GO:0009986 cell surface
GO:0071944 cell periphery
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000045871
View Gene Order
ENSBTAG00000004388
Not yet available
Pathways
NETPATH
NetPath_4
EGFR1 pathway
REACTOME
KEGG
INOH
PID NCI
Cross-References
SwissProt Q9H5Y7
TrEMBL
UniProt Splice Variant
Entrez Gene 84189
UniGene Hs.525105
RefSeq NM_032229
HUGO HGNC:23503
OMIM 609681
CCDS CCDS41903
HPRD 15403
IMGT
EMBL AK021931 AK026427 AK292793 AL137517 AL162373 BC101070 BC101071 BC101072 BC101073 BX648640 CH471093
GenPept AAI01071 AAI01072 AAI01073 AAI01074 BAB13941 BAB15480 BAF85482 CAB70783 CAH10557 EAW80611
RNA Seq Atlas 84189

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca