Version 5.4
Homo sapiens Gene: ZNF16
Summary
InnateDB Gene IDBG-41817.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ZNF16
Gene Name zinc finger protein 16
Synonyms HZF1; KOX9
Species Homo sapiens
Ensembl Gene ENSG00000170631
Encoded Proteins
IDBP-41819
zinc finger protein 16
IDBP-240634
zinc finger protein 16
IDBP-587602
zinc finger protein 16
IDBP-598975
zinc finger protein 16
IDBP-811529
zinc finger protein 16
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene contains multiple tandem zinc finger motifs. The encoded protein is involved in the differentiation of erythroid and megakaryocytic cells. This gene is located in a cluster of related genes on chromosome 8 encoding zinc finger proteins. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 8:144930358-144950888
Strand Reverse strand
Band q24.3
Transcripts
ENST00000276816 ENSP00000276816
ENST00000394909 ENSP00000378369
ENST00000532351 ENSP00000434321
ENST00000532811
ENST00000527512
ENST00000527811 ENSP00000432755
ENST00000527427
ENST00000529378
ENST00000611477 ENSP00000484504
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0005515 protein binding
GO:0046872 metal ion binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0007049 cell cycle
GO:0008284 positive regulation of cell proliferation
GO:0033674 positive regulation of kinase activity
GO:0043066 negative regulation of apoptotic process
GO:0045648 positive regulation of erythrocyte differentiation
GO:0045654 positive regulation of megakaryocyte differentiation
GO:0051301 cell division
GO:0051781 positive regulation of cell division
GO:0072707 cellular response to sodium dodecyl sulfate
GO:1901989 positive regulation of cell cycle phase transition
Cellular Component
GO:0005634 nucleus
Orthologs
No orthologs found for this gene
Cross-References
SwissProt
TrEMBL E9PNT9 E9PQV1 Q8ND22
UniProt Splice Variant
Entrez Gene 7564
UniGene
RefSeq NM_006958 NM_001029976 XM_005272341
HUGO HGNC:12947
OMIM 601262
CCDS CCDS6437
HPRD
IMGT
EMBL AF235103 AF244088 AK127625 AL834451 BC010996 CH471162 DQ117529 X52340
GenPept AAF75235 AAH10996 AAZ20773 BAG54536 CAA36566 CAD39111 EAW82027 EAW82028
RNA Seq Atlas 7564

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca