Version 5.4
Homo sapiens Gene: SLC35B4
Summary
InnateDB Gene IDBG-42112.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SLC35B4
Gene Name solute carrier family 35, member B4
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000205060
Encoded Proteins
IDBP-42114
solute carrier family 35, member B4
IDBP-386426
solute carrier family 35, member B4
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Glycosyltransferases, such as SLC35B4, transport nucleotide sugars from the cytoplasm where they are synthesized, to the Golgi apparatus where they are utilized in the synthesis of glycoproteins, glycolipids, and proteoglycans (Ashikov et al., 2005 [PubMed 15911612]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 7:134289332-134317051
Strand Reverse strand
Band q33
Transcripts
ENST00000378509 ENSP00000367770
ENST00000416907 ENSP00000405445
ENST00000466599
ENST00000470969
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 0
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005462 UDP-N-acetylglucosamine transmembrane transporter activity
GO:0005464 UDP-xylose transmembrane transporter activity
Biological Process
GO:0006111 regulation of gluconeogenesis
GO:0008643 carbohydrate transport
GO:0015788 UDP-N-acetylglucosamine transport
GO:0015790 UDP-xylose transport
GO:0055085 transmembrane transport
Cellular Component
GO:0000139 Golgi membrane
GO:0005794 Golgi apparatus
GO:0016021 integral component of membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000018999
View Gene Order
ENSBTAG00000003372
Not yet available
Pathways
NETPATH
REACTOME
REACT_22151
Transport of nucleotide sugars pathway
REACT_22285
Transport of vitamins, nucleosides, and related molecules pathway
REACT_15518
Transmembrane transport of small molecules pathway
REACT_19118
SLC-mediated transmembrane transport pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt Q969S0
TrEMBL F8WAW0
UniProt Splice Variant
Entrez Gene 84912
UniGene Hs.490181 Hs.599643
RefSeq NM_032826
HUGO HGNC:20584
OMIM 610923
CCDS CCDS34756
HPRD
IMGT
EMBL AB052892 AC008154 AJ315497 AJ315498 AJ971941 AK027603 AK027726 AK075368 AK222874 BC008413 CH236950 CH471070
GenPept AAH08413 BAB55225 BAB55325 BAB61040 BAC11573 BAD96594 CAC84567 CAC84568 CAI98963 EAL24071 EAW83810
RNA Seq Atlas 84912

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca