Version 5.4
Homo sapiens Protein: SLC35B4
Summary
InnateDB Protein IDBP-42114.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SLC35B4
Protein Name solute carrier family 35, member B4
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000367770
InnateDB Gene IDBG-42112 (SLC35B4)
Protein Structure
UniProt Annotation
Function Sugar transporter that specifically mediates the transport of UDP-xylose (UDP-Xyl) and UDP-N-acetylglucosamine (UDP-GlcNAc) from cytosol into Golgi. {ECO:0000269PubMed:15911612}.
Subcellular Localization Golgi apparatus membrane {ECO:0000269PubMed:15911612}; Multi-pass membrane protein {ECO:0000269PubMed:15911612}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 0
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005462 UDP-N-acetylglucosamine transmembrane transporter activity
GO:0005464 UDP-xylose transmembrane transporter activity
Biological Process
GO:0006111 regulation of gluconeogenesis
GO:0008643 carbohydrate transport
GO:0015788 UDP-N-acetylglucosamine transport
GO:0015790 UDP-xylose transport
GO:0055085 transmembrane transport
Cellular Component
GO:0000139 Golgi membrane
GO:0005794 Golgi apparatus
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro IPR004853 Triose-phosphate transporter domain
IPR013657 UAA transporter
PFAM PF03151
PF08449
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q969S0
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 84912
UniGene Hs.599643
RefSeq NP_116215
HUGO HGNC:20584
OMIM 610923
CCDS CCDS34756
HPRD 11578
IMGT
EMBL AB052892 AC008154 AJ315497 AJ315498 AJ971941 AK027603 AK027726 AK075368 AK222874 BC008413 CH236950 CH471070
GenPept AAH08413 BAB55225 BAB55325 BAB61040 BAC11573 BAD96594 CAC84567 CAC84568 CAI98963 EAL24071 EAW83810

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca