Version 5.4
Homo sapiens Gene: RHPN2
Summary
InnateDB Gene IDBG-42413.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol RHPN2
Gene Name rhophilin, Rho GTPase binding protein 2
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000131941
Encoded Proteins
IDBP-42415
rhophilin, Rho GTPase binding protein 2
IDBP-759722
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of the rhophilin family of Ras-homologous (Rho)-GTPase binding proteins. The encoded protein binds both GTP- and GDP-bound RhoA and GTP-bound RhoB and may be involved in the organization of the actin cytoskeleton. [provided by RefSeq, Apr 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 19:32978593-33064888
Strand Reverse strand
Band q13.11
Transcripts
ENST00000254260 ENSP00000254260
ENST00000544458
ENST00000585641
ENST00000588683
ENST00000591502
ENST00000592247
ENST00000588388 ENSP00000465898
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 10 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 10 [view]
Protein-Protein 10 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0007165 signal transduction
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0043231 intracellular membrane-bounded organelle
GO:0048471 perinuclear region of cytoplasm
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000030494
View Gene Order
ENSBTAG00000003089
Not yet available
Cross-References
SwissProt
TrEMBL K7EL35
UniProt Splice Variant
Entrez Gene 85415
UniGene Hs.466435 Hs.630796
RefSeq NM_033103
HUGO HGNC:19974
OMIM
CCDS CCDS12427
HPRD 10192
IMGT
EMBL AC008521 AC011449 AC093069
GenPept
RNA Seq Atlas 85415

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca