InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Gene: CHST5

Summary

InnateDB Gene

IDBG-42572.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

CHST5

Gene Name

carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5

Synonyms

glcNAc6ST-3; gn6st-3; hIGn6ST; I-GlcNAc-6-ST; I-GlcNAc6ST

Species

Homo sapiens

Ensembl Gene

ENSG00000135702

Encoded Proteins

IDBP-42574

carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5

IDBP-752847

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

The protein encoded by this gene belongs to the Gal/GalNAc/GlcNAc 6-O-sulfotransferase (GST) family, members of which catalyze the transfer of sulfate to position 6 of galactose (Gal), N-acetylgalactosamine (GalNAc), or N-acetylglucosamine (GlcNAc) residues within proteoglycans, and sulfation of O-linked sugars of mucin-type acceptors. Carbohydrate sulfation plays a critical role in many biologic processes. This gene is predominantly expressed in colon and small intestine. [provided by RefSeq, Aug 2011]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 16:75528535-75535247

Strand

Reverse strand

Band

q23.1

Transcripts

ENST00000336257	ENSP00000338783
ENST00000565039	ENSP00000454375

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0001517	N-acetylglucosamine 6-O-sulfotransferase activity
GO:0008146	sulfotransferase activity

Biological Process

GO:0005975	carbohydrate metabolic process
GO:0006044	N-acetylglucosamine metabolic process
GO:0006477	protein sulfation
GO:0006790	sulfur compound metabolic process
GO:0018146	keratan sulfate biosynthetic process
GO:0030203	glycosaminoglycan metabolic process
GO:0042339	keratan sulfate metabolic process
GO:0044281	small molecule metabolic process