InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Gene: KIF5A

Summary

InnateDB Gene

IDBG-42948.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

KIF5A

Gene Name

kinesin family member 5A

Synonyms

D12S1889; MY050; NKHC; SPG10

Species

Homo sapiens

Ensembl Gene

ENSG00000155980

Encoded Proteins

IDBP-42950

kinesin family member 5A

IDBP-378864

kinesin family member 5A

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene encodes a member of the kinesin family of proteins. Members of this family are part of a multisubunit complex that functions as a microtubule motor in intracellular organelle transport. Mutations in this gene cause autosomal dominant spastic paraplegia 10. [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 12:57549998-57586632

Strand

Forward strand

Band

q13.3

Transcripts

ENST00000286452	ENSP00000286452
ENST00000455537	ENSP00000408979
ENST00000552227

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 28 experimentally validated interaction(s) in this database.
They are also associated with 11 interaction(s) predicted by orthology.

Experimentally validated
Total	28 [view]
Protein-Protein	28 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	11 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003774	motor activity
GO:0003777	microtubule motor activity
GO:0005515	protein binding
GO:0005524	ATP binding
GO:0008017	microtubule binding

Biological Process

GO:0007018	microtubule-based movement
GO:0007268	synaptic transmission
GO:0007596	blood coagulation
GO:0008152	metabolic process
GO:0008219	cell death
GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II