Version 5.4
Homo sapiens Gene: LEAP2
Summary
InnateDB Gene IDBG-43708.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol LEAP2
Gene Name liver expressed antimicrobial peptide 2
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000164406
Encoded Proteins
IDBP-43712
liver expressed antimicrobial peptide 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary LEAP2 is a cysteine-rich cationic antimicrobial peptide (Krause et al., 2003 [PubMed 12493837]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 5:132872322-132875046
Strand Forward strand
Band q31.1
Transcripts
ENST00000296877 ENSP00000296877
ENST00000483190
ENST00000485457
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 0
Protein-DNA 0
Protein-RNA 0
DNA-DNA 1 [view]
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0042742 defense response to bacterium
Cellular Component
GO:0005576 extracellular region
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000036216
View Gene Order
ENSBTAG00000018926
Not yet available
Cross-References
SwissProt Q969E1
TrEMBL
UniProt Splice Variant
Entrez Gene 116842
UniGene Hs.337588
RefSeq NM_052971
HUGO HGNC:29571
OMIM 611373
CCDS CCDS4163
HPRD 17269
IMGT
EMBL AJ306405 AJ409064 AJ409065 BC070199 CH471062
GenPept AAH70199 CAC51306 CAC51515 CAC51516 EAW62306 EAW62307
RNA Seq Atlas 116842

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca