Version 5.4
Homo sapiens Protein: LEAP2
Summary
InnateDB Protein IDBP-43712.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol LEAP2
Protein Name liver expressed antimicrobial peptide 2
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000296877
InnateDB Gene IDBG-43708 (LEAP2)
Protein Structure
UniProt Annotation
Function Has an antimicrobial activity. {ECO:0000269PubMed:20845358}.
Subcellular Localization Secreted.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 0
Protein-DNA 0
Protein-RNA 0
DNA-DNA 1 [view]
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0042742 defense response to bacterium
Cellular Component
GO:0005576 extracellular region
Protein Structure and Domains
PDB ID
InterPro IPR009955 Liver-expressed antimicrobial peptide 2
PFAM PF07359
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q969E1
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 116842
UniGene Hs.337588
RefSeq NP_443203
HUGO HGNC:29571
OMIM 611373
CCDS CCDS4163
HPRD 17269
IMGT
EMBL AJ306405 AJ409064 AJ409065 BC070199 CH471062
GenPept AAH70199 CAC51306 CAC51515 CAC51516 EAW62306 EAW62307

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca