Version 5.4
Homo sapiens Gene: TMF1
Summary
InnateDB Gene IDBG-43864.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TMF1
Gene Name TATA element modulatory factor 1
Synonyms ARA160; TMF
Species Homo sapiens
Ensembl Gene ENSG00000144747
Encoded Proteins
IDBP-232792
TATA element modulatory factor 1
IDBP-478373
TATA element modulatory factor 1
IDBP-600836
TATA element modulatory factor 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 3:69019827-69052303
Strand Reverse strand
Band p14.1
Transcripts
ENST00000398559 ENSP00000381567
ENST00000488010 ENSP00000419330
ENST00000489370
ENST00000477872
ENST00000543976 ENSP00000438706
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 15 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Experimentally validated
Total 15 [view]
Protein-Protein 11 [view]
Protein-DNA 4 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0003712 transcription cofactor activity
GO:0005515 protein binding
Biological Process
GO:0001675 acrosome assembly
GO:0001819 positive regulation of cytokine production
GO:0006355 regulation of transcription, DNA-templated
GO:0006366 transcription from RNA polymerase II promoter
GO:0007286 spermatid development
GO:0007289 spermatid nucleus differentiation
GO:0008584 male gonad development
GO:0010629 negative regulation of gene expression
GO:0030317 sperm motility
GO:0032275 luteinizing hormone secretion
GO:0033327 Leydig cell differentiation
GO:0042742 defense response to bacterium
GO:0043066 negative regulation of apoptotic process
GO:0061136 regulation of proteasomal protein catabolic process
GO:0071407 cellular response to organic cyclic compound
GO:2000845 positive regulation of testosterone secretion
Cellular Component
GO:0000139 Golgi membrane
GO:0005634 nucleus
GO:0005783 endoplasmic reticulum
GO:0005794 Golgi apparatus
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000030059
View Gene Order
ENSBTAG00000015554
Not yet available
Pathways
NETPATH
NetPath_2
AndrogenReceptor pathway
REACTOME
KEGG
INOH
PID NCI
ar_pathway
Coregulation of Androgen receptor activity
Cross-References
SwissProt
TrEMBL F8WF45
UniProt Splice Variant
Entrez Gene 7110
UniGene Hs.267632 Hs.598046 Hs.694341
RefSeq NM_007114
HUGO HGNC:11870
OMIM 601126
CCDS CCDS43105
HPRD 03081
IMGT
EMBL AC109587
GenPept
RNA Seq Atlas 7110

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca