Version 5.4
Homo sapiens Gene: DENND2A
Summary
InnateDB Gene IDBG-44191.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol DENND2A
Gene Name DENN/MADD domain containing 2A
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000146966
Encoded Proteins
IDBP-44193
DENN/MADD domain containing 2A
IDBP-482417
DENN/MADD domain containing 2A
IDBP-477794
DENN/MADD domain containing 2A
IDBP-475223
DENN/MADD domain containing 2A
IDBP-473499
DENN/MADD domain containing 2A
IDBP-484498
DENN/MADD domain containing 2A
IDBP-484045
DENN/MADD domain containing 2A
IDBP-483913
DENN/MADD domain containing 2A
IDBP-476310
DENN/MADD domain containing 2A
IDBP-585320
DENN/MADD domain containing 2A
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 7:140518420-140673993
Strand Reverse strand
Band q34
Transcripts
ENST00000275884 ENSP00000275884
ENST00000461883 ENSP00000417673
ENST00000496613 ENSP00000419654
ENST00000469373 ENSP00000420145
ENST00000492720 ENSP00000419464
ENST00000475837 ENSP00000420605
ENST00000491728 ENSP00000418844
ENST00000489552 ENSP00000418088
ENST00000477488 ENSP00000418760
ENST00000537639 ENSP00000442245
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0017112 Rab guanyl-nucleotide exchange factor activity
Biological Process
GO:0015031 protein transport
GO:0032851 positive regulation of Rab GTPase activity
GO:0042147 retrograde transport, endosome to Golgi
Cellular Component
GO:0005737 cytoplasm
GO:0015629 actin cytoskeleton
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000038456
View Gene Order
ENSBTAG00000004799
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.6385
RefSeq NM_015689 XM_005249976 XM_005249977 XM_005249978 XM_005249979
HUGO
OMIM
CCDS CCDS43659
HPRD 17210
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca