Version 5.4
Homo sapiens Gene: RYBP
Summary
InnateDB Gene IDBG-44775.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol RYBP
Gene Name RING1 and YY1 binding protein
Synonyms AAP1; DEDAF; YEAF1
Species Homo sapiens
Ensembl Gene ENSG00000163602
Encoded Proteins
IDBP-483111
RING1 and YY1 binding protein
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 3:72371825-72446918
Strand Reverse strand
Band p13
Transcripts
ENST00000477973 ENSP00000419494
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 60 experimentally validated interaction(s) in this database.
They are also associated with 17 interaction(s) predicted by orthology.
Experimentally validated
Total 60 [view]
Protein-Protein 59 [view]
Protein-DNA 0
Protein-RNA 1 [view]
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 17 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0003714 transcription corepressor activity
GO:0005515 protein binding
GO:0008270 zinc ion binding
Biological Process
GO:0000122 negative regulation of transcription from RNA polymerase II promoter
GO:0006351 transcription, DNA-templated
GO:0006915 apoptotic process
GO:0007275 multicellular organismal development
GO:0035518 histone H2A monoubiquitination
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0031519 PcG protein complex
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000072872
View Gene Order
ENSBTAG00000022689
Not yet available
Pathways
NETPATH
REACTOME
KEGG
INOH
PID NCI
e2f_pathway
E2F transcription factor network
Cross-References
SwissProt Q8N488
TrEMBL
UniProt Splice Variant
Entrez Gene 23429
UniGene Hs.612472 Hs.623260 Hs.7910
RefSeq NM_012234
HUGO HGNC:10480
OMIM 607535
CCDS
HPRD 09607
IMGT
EMBL AB029551 AF179286 AF227959 AY228125 BC014959 BC036459
GenPept AAD51858 AAH14959 AAH36459 AAK63197 AAO73587 BAA89486
RNA Seq Atlas 23429

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca