Version 5.4
Homo sapiens Gene: ETV2
Summary
InnateDB Gene IDBG-44778.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ETV2
Gene Name ets variant 2
Synonyms ER71; ETSRP71
Species Homo sapiens
Ensembl Gene ENSG00000105672
Encoded Proteins
IDBP-44780
ets variant 2
IDBP-44784
ets variant 2
IDBP-295247
ets variant 2
IDBP-295242
ets variant 2
IDBP-763548
IDBP-810789
ets variant 2
IDBP-810791
ets variant 2
IDBP-810792
ets variant 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 19:35641745-35644871
Strand Forward strand
Band q13.12
Transcripts
ENST00000379026 ENSP00000368312
ENST00000379023 ENSP00000368309
ENST00000402764 ENSP00000384524
ENST00000403402 ENSP00000385369
ENST00000479824 ENSP00000468453
ENST00000591135 ENSP00000475089
ENST00000621247 ENSP00000480641
ENST00000619399 ENSP00000477924
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0000981 sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0001077 RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0001701 in utero embryonic development
GO:0001707 mesoderm formation
GO:0001824 blastocyst development
GO:0001890 placenta development
GO:0006355 regulation of transcription, DNA-templated
GO:0006357 regulation of transcription from RNA polymerase II promoter
GO:0006366 transcription from RNA polymerase II promoter
GO:0007219 Notch signaling pathway
GO:0010628 positive regulation of gene expression
GO:0016055 Wnt signaling pathway
GO:0030097 hemopoiesis
GO:0030154 cell differentiation
GO:0030218 erythrocyte differentiation
GO:0045603 positive regulation of endothelial cell differentiation
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
GO:0048514 blood vessel morphogenesis
GO:0060803 BMP signaling pathway involved in mesodermal cell fate specification
GO:2000382 positive regulation of mesoderm development
Cellular Component
GO:0005634 nucleus
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000006311
View Gene Order
ENSBTAG00000013444
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene 2116
UniGene
RefSeq NM_001300974 NM_014209 XM_005258652 XM_005258654
HUGO HGNC:3491
OMIM 609358
CCDS CCDS32995 CCDS74341
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas 2116

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca