Version 5.4
Homo sapiens Gene: INPP5J
Summary
InnateDB Gene IDBG-4479.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol INPP5J
Gene Name inositol polyphosphate-5-phosphatase J
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000185133
Encoded Proteins
IDBP-4481
inositol polyphosphate-5-phosphatase J
IDBP-228593
inositol polyphosphate-5-phosphatase J
IDBP-294406
inositol polyphosphate-5-phosphatase J
IDBP-294412
inositol polyphosphate-5-phosphatase J
IDBP-294407
inositol polyphosphate-5-phosphatase J
IDBP-294409
inositol polyphosphate-5-phosphatase J
IDBP-294404
inositol polyphosphate-5-phosphatase J
IDBP-372555
inositol polyphosphate-5-phosphatase J
IDBP-372589
inositol polyphosphate-5-phosphatase J
IDBP-372605
inositol polyphosphate-5-phosphatase J
IDBP-812761
inositol polyphosphate-5-phosphatase J
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 22:31122731-31134696
Strand Forward strand
Band q12.2
Transcripts
ENST00000331075 ENSP00000333262
ENST00000400294 ENSP00000383150
ENST00000404390 ENSP00000384534
ENST00000405300 ENSP00000384596
ENST00000402238 ENSP00000385264
ENST00000404453 ENSP00000385343
ENST00000401755 ENSP00000384540
ENST00000412985 ENSP00000401124
ENST00000420017 ENSP00000406570
ENST00000412277 ENSP00000392924
ENST00000463528
ENST00000461241
ENST00000620191 ENSP00000479645
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0004445 inositol-polyphosphate 5-phosphatase activity
GO:0017124 SH3 domain binding
GO:0034485 phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity
GO:0052658 inositol-1,4,5-trisphosphate 5-phosphatase activity
GO:0052659 inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity
Biological Process
GO:0006644 phospholipid metabolic process
GO:0006661 phosphatidylinositol biosynthetic process
GO:0010977 negative regulation of neuron projection development
GO:0031115 negative regulation of microtubule polymerization
GO:0033137 negative regulation of peptidyl-serine phosphorylation
GO:0043647 inositol phosphate metabolic process
GO:0044281 small molecule metabolic process
GO:0046856 phosphatidylinositol dephosphorylation
Cellular Component
GO:0001726 ruffle
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0030426 growth cone
GO:0043198 dendritic shaft
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000034570
View Gene Order
ENSBTAG00000017023
Not yet available
Pathways
NETPATH
REACTOME
REACT_121025
Synthesis of PIPs at the plasma membrane pathway
REACT_150352
Synthesis of IP2, IP, and Ins in the cytosol pathway
REACT_150312
Synthesis of IP3 and IP4 in the cytosol pathway
REACT_22258
Metabolism of lipids and lipoproteins pathway
REACT_121175
PI Metabolism pathway
REACT_120870
Phospholipid metabolism pathway
REACT_150154
Inositol phosphate metabolism pathway
REACT_111217
Metabolism pathway
KEGG
hsa00562
Inositol phosphate metabolism pathway
hsa04070
Phosphatidylinositol signaling system pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq NM_001002837 NM_001284285 NM_001284286 NM_001284287 NM_001284288 NM_001284289 XM_006724230
HUGO
OMIM
CCDS CCDS46687 CCDS63453 CCDS63454 CCDS63455 CCDS74847
HPRD 07573
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca