Version 5.4
Homo sapiens Gene: SERPINB4
Summary
InnateDB Gene IDBG-4510.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SERPINB4
Gene Name serpin peptidase inhibitor, clade B (ovalbumin), member 4
Synonyms LEUPIN; PI11; SCCA-2; SCCA1; SCCA2
Species Homo sapiens
Ensembl Gene ENSG00000206073
Encoded Proteins
IDBP-4512
serpin peptidase inhibitor, clade B (ovalbumin), member 4
IDBP-4514
serpin peptidase inhibitor, clade B (ovalbumin), member 4
IDBP-371929
serpin peptidase inhibitor, clade B (ovalbumin), member 4
IDBP-371930
serpin peptidase inhibitor, clade B (ovalbumin), member 4
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 18:63637259-63644298
Strand Reverse strand
Band q21.33
Transcripts
ENST00000341074 ENSP00000343445
ENST00000356424 ENSP00000348795
ENST00000413673 ENSP00000398645
ENST00000436264 ENSP00000399796
ENST00000498496
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 12 experimentally validated interaction(s) in this database.
Experimentally validated
Total 12 [view]
Protein-Protein 12 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004867 serine-type endopeptidase inhibitor activity
GO:0019899 enzyme binding
Biological Process
GO:0010466 negative regulation of peptidase activity
GO:0010951 negative regulation of endopeptidase activity
GO:0030162 regulation of proteolysis
Cellular Component
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005737 cytoplasm
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Mus musculus
Gene ID
Gene Order
ENSMUSG00000044594
View Gene Order
Pathways
NETPATH
REACTOME
KEGG
hsa05146
Amoebiasis pathway
INOH
PID NCI
Cross-References
SwissProt P48594
TrEMBL
UniProt Splice Variant
Entrez Gene 6318
UniGene Hs.123035
RefSeq NM_002974 NM_175041 NM_006919
HUGO HGNC:10570
OMIM 600518
CCDS CCDS11986 CCDS11987
HPRD 02746
IMGT
EMBL AB035089 AK292212 BC017401 U19557 U19570 U19571 U19572 U19574 U19575 U19576 X89015
GenPept AAA92602 AAA97553 AAH17401 BAB21525 BAF84901 CAA61420
RNA Seq Atlas 6318

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca