Homo sapiens Gene: GINS2
Summary
InnateDB Gene IDBG-45117.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol GINS2
Gene Name GINS complex subunit 2 (Psf2 homolog)
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000131153
Encoded Proteins
GINS complex subunit 2 (Psf2 homolog)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The yeast heterotetrameric GINS complex is made up of Sld5 (GINS4; MIM 610611), Psf1 (GINS1; MIM 610608), Psf2, and Psf3 (GINS3; MIM 610610). The formation of this complex is essential for the initiation of DNA replication in yeast and Xenopus egg extracts (Ueno et al., 2005 [PubMed 16287864]). See GINS1 for additional information about the GINS complex.[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 16:85676198-85690073
Strand Reverse strand
Band q24.1
Transcripts
ENST00000253462 ENSP00000253462
ENST00000595355 ENSP00000470984
ENST00000596233 ENSP00000469346
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 25 experimentally validated interaction(s) in this database.
Experimentally validated
Total 25 [view]
Protein-Protein 24 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0000278 mitotic cell cycle
GO:0006260 DNA replication
GO:0006271 DNA strand elongation involved in DNA replication
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Not yet available
Pathways
NETPATH
REACTOME
Unwinding of DNA pathway
DNA Replication pathway
Synthesis of DNA pathway
S Phase pathway
Cell Cycle pathway
Cell Cycle, Mitotic pathway
DNA strand elongation pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL M0QXS3 M0R043
UniProt Splice Variant
Entrez Gene 51659
UniGene Hs.602488
RefSeq NM_016095
HUGO HGNC:24575
OMIM 610609
CCDS CCDS10953
HPRD 15197
IMGT
EMBL AC123908
GenPept
RNA Seq Atlas 51659