Version 5.4
Homo sapiens Gene: MYL12A
Summary
InnateDB Gene IDBG-452.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MYL12A
Gene Name myosin, light chain 12A, regulatory, non-sarcomeric
Synonyms HEL-S-24; MLCB; MRCL3; MRLC3; MYL2B
Species Homo sapiens
Ensembl Gene ENSG00000101608
Encoded Proteins
IDBP-454
myosin, light chain 12A, regulatory, non-sarcomeric
IDBP-595093
myosin, light chain 12A, regulatory, non-sarcomeric
IDBP-727739
IDBP-726482
IDBP-726318
IDBP-726544
IDBP-727505
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 18:3247481-3256236
Strand Forward strand
Band p11.31
Transcripts
ENST00000217652 ENSP00000217652
ENST00000536605 ENSP00000441231
ENST00000583449 ENSP00000462865
ENST00000578562 ENSP00000463009
ENST00000578038
ENST00000585090
ENST00000579226 ENSP00000462171
ENST00000580353
ENST00000580887 ENSP00000464359
ENST00000578611 ENSP00000463614
ENST00000577510
ENST00000608786
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 51 experimentally validated interaction(s) in this database.
Experimentally validated
Total 51 [view]
Protein-Protein 51 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005509 calcium ion binding
GO:0005515 protein binding
GO:0035254 glutamate receptor binding
Biological Process
GO:0008360 regulation of cell shape
GO:0072661 protein targeting to plasma membrane
Cellular Component
GO:0001725 stress fiber
GO:0016460 myosin II complex
GO:0030018 Z disc
GO:0043234 protein complex
GO:0070062 extracellular vesicular exosome
Orthologs
No orthologs found for this gene
Pathways
NETPATH
NetPath_4
EGFR1 pathway
REACTOME
REACT_111045
Developmental Biology pathway
REACT_18266
Axon guidance pathway
REACT_228226
Ephrin signaling pathway
REACT_228170
EPH-Ephrin signaling pathway
KEGG
hsa04810
Regulation of actin cytoskeleton pathway
hsa04670
Leukocyte transendothelial migration pathway
hsa04530
Tight junction pathway
hsa04510
Focal adhesion pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.190086 Hs.627091 Hs.734070
RefSeq NM_006471 XM_005258076 XM_005258077
HUGO
OMIM
CCDS CCDS11830
HPRD 14735
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca