Version 5.4
Homo sapiens Gene: GPM6B
Summary
InnateDB Gene IDBG-45290.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol GPM6B
Gene Name glycoprotein M6B
Synonyms M6B
Species Homo sapiens
Ensembl Gene ENSG00000046653
Encoded Proteins
IDBP-45292
glycoprotein M6B
IDBP-45294
glycoprotein M6B
IDBP-45296
glycoprotein M6B
IDBP-233219
glycoprotein M6B
IDBP-362289
glycoprotein M6B
IDBP-480707
glycoprotein M6B
IDBP-476409
glycoprotein M6B
IDBP-476999
glycoprotein M6B
IDBP-483669
glycoprotein M6B
IDBP-483114
glycoprotein M6B
IDBP-476021
glycoprotein M6B
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a membrane glycoprotein that belongs to the proteolipid protein family. Proteolipid protein family members are expressed in most brain regions and are thought to be involved in cellular housekeeping functions, such as membrane trafficking and cell-to-cell communication. [provided by RefSeq, Apr 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome X:13771031-13938638
Strand Reverse strand
Band p22.2
Transcripts
ENST00000316715 ENSP00000316861
ENST00000356942 ENSP00000349420
ENST00000355135 ENSP00000347258
ENST00000398361 ENSP00000381402
ENST00000454189 ENSP00000389915
ENST00000493677 ENSP00000419904
ENST00000472735 ENSP00000419921
ENST00000495211 ENSP00000419409
ENST00000493085 ENSP00000418199
ENST00000468080 ENSP00000419779
ENST00000475307 ENSP00000418594
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
Biological Process
GO:0001503 ossification
GO:0007399 nervous system development
GO:0015031 protein transport
GO:0030154 cell differentiation
GO:0030501 positive regulation of bone mineralization
GO:0032956 regulation of actin cytoskeleton organization
GO:0051612 negative regulation of serotonin uptake
GO:0051893 regulation of focal adhesion assembly
GO:0085029 extracellular matrix assembly
GO:2000009 negative regulation of protein localization to cell surface
Cellular Component
GO:0005886 plasma membrane
GO:0016021 integral component of membrane
GO:0045121 membrane raft
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000031342
View Gene Order
ENSBTAG00000009260
Not yet available
Cross-References
SwissProt
TrEMBL B7Z248 C9J8H8 C9JZE8
UniProt Splice Variant
Entrez Gene 2824
UniGene Hs.495710 Hs.618017 Hs.732644
RefSeq NM_001001994 NM_001001995 NM_001001996 NM_005278
HUGO HGNC:4461
OMIM 300051
CCDS CCDS14158 CCDS35206 CCDS35207 CCDS48084
HPRD 02082
IMGT
EMBL AC003035 AC003037 AK294314
GenPept BAH11734
RNA Seq Atlas 2824

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca