Version 5.4
Homo sapiens Gene: DOCK9
Summary
InnateDB Gene IDBG-45550.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol DOCK9
Gene Name dedicator of cytokinesis 9
Synonyms ZIZ1; ZIZIMIN1
Species Homo sapiens
Ensembl Gene ENSG00000088387
Encoded Proteins
IDBP-45552
dedicator of cytokinesis 9
IDBP-45558
dedicator of cytokinesis 9
IDBP-45562
dedicator of cytokinesis 9
IDBP-228657
dedicator of cytokinesis 9
IDBP-372627
dedicator of cytokinesis 9
IDBP-372629
dedicator of cytokinesis 9
IDBP-372634
dedicator of cytokinesis 9
IDBP-372719
dedicator of cytokinesis 9
IDBP-372724
dedicator of cytokinesis 9
IDBP-372726
dedicator of cytokinesis 9
IDBP-372727
dedicator of cytokinesis 9
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 13:98793487-99086625
Strand Reverse strand
Band q32.3
Transcripts
ENST00000376460 ENSP00000365643
ENST00000339416 ENSP00000341086
ENST00000340449 ENSP00000344702
ENST00000400228 ENSP00000383087
ENST00000448493 ENSP00000401958
ENST00000419908 ENSP00000388193
ENST00000451563 ENSP00000407610
ENST00000449796 ENSP00000403528
ENST00000450257 ENSP00000396897
ENST00000442173 ENSP00000406883
ENST00000427887 ENSP00000413781
ENST00000481051
ENST00000472874
ENST00000461998
ENST00000473165
ENST00000479769
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 8 [view]
Protein-Protein 7 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005085 guanyl-nucleotide exchange factor activity
GO:0005089 Rho guanyl-nucleotide exchange factor activity
GO:0005488 binding
GO:0005515 protein binding
GO:0017048 Rho GTPase binding
Biological Process
GO:0007264 small GTPase mediated signal transduction
GO:0007596 blood coagulation
GO:0008150 biological_process
GO:0032319 regulation of Rho GTPase activity
GO:0043547 positive regulation of GTPase activity
Cellular Component
GO:0005575 cellular_component
GO:0005829 cytosol
GO:0012505 endomembrane system
GO:0016020 membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000025558
View Gene Order
ENSBTAG00000010395
Not yet available
Pathways
NETPATH
REACTOME
REACT_24970
Factors involved in megakaryocyte development and platelet production pathway
REACT_604
Hemostasis pathway
KEGG
INOH
INOH website
Integrin signaling pathway pathway
PID NCI
cdc42_reg_pathway
Regulation of CDC42 activity
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.596105
RefSeq NM_001130048 NM_001130049 NM_001130050 NM_015296 XM_005254036 XM_006719928 XM_006719931 XM_006719932 XM_006719936 XM_006719937
HUGO
OMIM
CCDS CCDS45062
HPRD 09542
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca