Homo sapiens Gene: FBXL20
Summary
InnateDB Gene IDBG-45587.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol FBXL20
Gene Name F-box and leucine-rich repeat protein 20
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000108306
Encoded Proteins
F-box and leucine-rich repeat protein 20
F-box and leucine-rich repeat protein 20
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Members of the F-box protein family, such as FBXL20, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 17:39252644-39402523
Strand Reverse strand
Band q12
Transcripts
ENST00000264658 ENSP00000264658
ENST00000394294 ENSP00000377832
ENST00000581781 ENSP00000463132
ENST00000577399 ENSP00000462878
ENST00000583610 ENSP00000462271
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 5 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0001662 behavioral fear response
Cellular Component
GO:0005737 cytoplasm
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Not yet available
Cross-References
SwissProt
TrEMBL J3QKL3
UniProt Splice Variant
Entrez Gene 84961
UniGene Hs.462946
RefSeq NM_001184906 NM_032875 XM_005257746 XM_005257747
HUGO HGNC:24679
OMIM 609086
CCDS CCDS32640 CCDS54116
HPRD 10951
IMGT
EMBL AC005288 AC015910
GenPept
RNA Seq Atlas 84961