Version 5.4
Homo sapiens Protein: FBXL20
Summary
InnateDB Protein IDBP-241879.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol FBXL20
Protein Name F-box and leucine-rich repeat protein 20
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000377832
InnateDB Gene IDBG-45587 (FBXL20)
Protein Structure
UniProt Annotation
Function Substrate-recognition component of the SCF (SKP1-CUL1-F- box protein)-type E3 ubiquitin ligase complex. Role in neural transmission (By similarity). {ECO:0000250}.
Subcellular Localization Cytoplasm {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 5 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
Cellular Component
GO:0005737 cytoplasm
Protein Structure and Domains
PDB ID
InterPro IPR001810 F-box domain
IPR006553 Leucine-rich repeat, cysteine-containing subtype
PFAM PF00646
PF12937
PF13013
PRINTS
PIRSF
SMART SM00256
SM00367
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q96IG2
PhosphoSite PhosphoSite-Q96IG2
TrEMBL
UniProt Splice Variant
Entrez Gene 84961
UniGene Hs.462946
RefSeq NP_001171835
HUGO HGNC:24679
OMIM 609086
CCDS CCDS54116
HPRD 10951
IMGT
EMBL AK291844 BC007557 DQ223959
GenPept AAH07557 ABB03906 BAF84533

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca