Version 5.4
Homo sapiens Gene: NEUROG1
Summary
InnateDB Gene IDBG-45658.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol NEUROG1
Gene Name neurogenin 1
Synonyms AKA; bHLHa6; Math4C; NEUROD3; ngn1
Species Homo sapiens
Ensembl Gene ENSG00000181965
Encoded Proteins
IDBP-45660
neurogenin 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 5:135534282-135535949
Strand Reverse strand
Band q31.1
Transcripts
ENST00000314744 ENSP00000317580
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 10 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Experimentally validated
Total 10 [view]
Protein-Protein 6 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 4 [view]
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000989 transcription factor binding transcription factor activity
GO:0003677 DNA binding
GO:0003682 chromatin binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0005515 protein binding
GO:0046983 protein dimerization activity
GO:0070888 E-box binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006357 regulation of transcription from RNA polymerase II promoter
GO:0007399 nervous system development
GO:0022008 neurogenesis
GO:0030182 neuron differentiation
GO:0031536 positive regulation of exit from mitosis
GO:0042472 inner ear morphogenesis
GO:0045165 cell fate commitment
GO:0045664 regulation of neuron differentiation
GO:0045666 positive regulation of neuron differentiation
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
GO:0051091 positive regulation of sequence-specific DNA binding transcription factor activity
Cellular Component
GO:0005634 nucleus
GO:0043025 neuronal cell body
GO:0043204 perikaryon
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000048904
View Gene Order
ENSBTAG00000003331
Not yet available
Pathways
NETPATH
REACTOME
KEGG
INOH
PID NCI
betacatenin_nuc_pathway
Regulation of nuclear beta catenin signaling and target gene transcription
Cross-References
SwissProt Q92886
TrEMBL F1T0H3
UniProt Splice Variant
Entrez Gene 4762
UniGene Hs.248149
RefSeq NM_006161
HUGO HGNC:7764
OMIM 601726
CCDS CCDS4187
HPRD
IMGT
EMBL AB593107 BC008687 BC028226 BT019366 CH471062 U63842
GenPept AAB37575 AAH08687 AAH28226 AAV38173 BAJ84047 EAW62214
RNA Seq Atlas 4762

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca