Version 5.4
Homo sapiens Gene: TRPC7
Summary
InnateDB Gene IDBG-45985.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TRPC7
Gene Name transient receptor potential cation channel, subfamily C, member 7
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000069018
Encoded Proteins
IDBP-45991
transient receptor potential cation channel, subfamily C, member 7
IDBP-45993
transient receptor potential cation channel, subfamily C, member 7
IDBP-478931
transient receptor potential cation channel, subfamily C, member 7
IDBP-476577
transient receptor potential cation channel, subfamily C, member 7
IDBP-485032
transient receptor potential cation channel, subfamily C, member 7
IDBP-480871
transient receptor potential cation channel, subfamily C, member 7
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 5:136213320-136365537
Strand Reverse strand
Band q31.1
Transcripts
ENST00000378459 ENSP00000367720
ENST00000352189 ENSP00000330322
ENST00000513104 ENSP00000426070
ENST00000509288
ENST00000503275 ENSP00000421571
ENST00000514963 ENSP00000426870
ENST00000502753 ENSP00000424854
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
Experimentally validated
Total 5 [view]
Protein-Protein 5 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005216 ion channel activity
GO:0005262 calcium channel activity
GO:0005488 binding
GO:0005515 protein binding
Biological Process
GO:0006811 ion transport
GO:0006816 calcium ion transport
GO:0006828 manganese ion transport
GO:0007411 axon guidance
GO:0007596 blood coagulation
GO:0030168 platelet activation
GO:0034220 ion transmembrane transport
GO:0055085 transmembrane transport
GO:0070588 calcium ion transmembrane transport
Cellular Component
GO:0005635 nuclear envelope
GO:0005801 cis-Golgi network
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0048471 perinuclear region of cytoplasm
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000021541
View Gene Order
ENSBTAG00000014638
Not yet available
Pathways
NETPATH
REACTOME
REACT_160189
Stimuli-sensing channels pathway
REACT_162
Elevation of cytosolic Ca2+ levels pathway
REACT_23876
Platelet homeostasis pathway
REACT_2202
Effects of PIP2 hydrolysis pathway
REACT_18283
G alpha (q) signalling events pathway
REACT_120966
Gastrin-CREB signalling pathway via PKC and MAPK pathway
REACT_22228
Role of second messengers in netrin-1 signaling pathway
REACT_22237
Netrin-1 signaling pathway
REACT_15518
Transmembrane transport of small molecules pathway
REACT_111045
Developmental Biology pathway
REACT_23905
Platelet calcium homeostasis pathway
REACT_14797
Signaling by GPCR pathway
REACT_798
Platelet activation, signaling and aggregation pathway
REACT_18266
Axon guidance pathway
REACT_111102
Signal Transduction pathway
REACT_19184
GPCR downstream signaling pathway
REACT_25300
Ion channel transport pathway
REACT_169333
TRP channels pathway
REACT_604
Hemostasis pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.591263
RefSeq NM_001167576 NM_001167577 NM_020389 XM_005272036
HUGO
OMIM
CCDS CCDS47267 CCDS54905 CCDS54906
HPRD 18228
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca