Version 5.4
Homo sapiens Gene: ZRSR2
Summary
InnateDB Gene IDBG-46935.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ZRSR2
Gene Name zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 2
Synonyms U2AF1-RS2; U2AF1L2; U2AF1RS2; URP
Species Homo sapiens
Ensembl Gene ENSG00000169249
Encoded Proteins
IDBP-46937
zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 2
IDBP-46939
zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes an essential splicing factor. The encoded protein associates with the U2 auxiliary factor heterodimer, which is required for the recognition of a functional 3' splice site in pre-mRNA splicing, and may play a role in network interactions during spliceosome assembly. [provided by RefSeq, Jul 2008]
This gene encodes an essential splicing factor. The encoded protein associates with the U2 auxiliary factor heterodimer, which is required for the recognition of a functional 3\' splice site in pre-mRNA splicing, and may play a role in network interactions during spliceosome assembly. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome X:15790472-15823260
Strand Forward strand
Band p22.2
Transcripts
ENST00000307771 ENSP00000303015
ENST00000380308 ENSP00000369664
ENST00000468028
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 41 experimentally validated interaction(s) in this database.
Experimentally validated
Total 41 [view]
Protein-Protein 41 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0003676 nucleic acid binding
GO:0003723 RNA binding
GO:0005515 protein binding
GO:0030628 pre-mRNA 3'-splice site binding
GO:0046872 metal ion binding
Biological Process
GO:0000245 spliceosomal complex assembly
GO:0000398 mRNA splicing, via spliceosome
GO:0008380 RNA splicing
Cellular Component
GO:0005634 nucleus
GO:0005689 U12-type spliceosomal complex
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000031370
View Gene Order
ENSBTAG00000020419
Not yet available
Cross-References
SwissProt Q15696
TrEMBL A6NDW0
UniProt Splice Variant
Entrez Gene 8233
UniGene Hs.171909 Hs.631208
RefSeq NM_005089 XM_005274597 XM_006724520
HUGO HGNC:23019
OMIM 300028
CCDS CCDS14172
HPRD
IMGT
EMBL AC004106 AC096510 BC113454 BC113480 D49677
GenPept AAI13455 AAI13481 BAA08533
RNA Seq Atlas 8233

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca