Version 5.4
Homo sapiens Gene: RAPGEFL1
Summary
InnateDB Gene IDBG-47265.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol RAPGEFL1
Gene Name Rap guanine nucleotide exchange factor (GEF)-like 1
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000108352
Encoded Proteins
IDBP-47267
Rap guanine nucleotide exchange factor (GEF)-like 1
IDBP-377668
Rap guanine nucleotide exchange factor (GEF)-like 1
IDBP-589805
Rap guanine nucleotide exchange factor (GEF)-like 1
IDBP-599304
Rap guanine nucleotide exchange factor (GEF)-like 1
IDBP-588650
Rap guanine nucleotide exchange factor (GEF)-like 1
IDBP-585268
Rap guanine nucleotide exchange factor (GEF)-like 1
IDBP-585916
Rap guanine nucleotide exchange factor (GEF)-like 1
IDBP-812021
Rap guanine nucleotide exchange factor (GEF)-like 1
IDBP-812025
Rap guanine nucleotide exchange factor (GEF)-like 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 17:40177010-40195656
Strand Forward strand
Band q21.1
Transcripts
ENST00000264644 ENSP00000264644
ENST00000456989 ENSP00000394530
ENST00000469209
ENST00000496032
ENST00000543876 ENSP00000440226
ENST00000544503 ENSP00000438631
ENST00000538884 ENSP00000440006
ENST00000541245 ENSP00000444646
ENST00000538981 ENSP00000441059
ENST00000545893
ENST00000613811 ENSP00000484772
ENST00000620260 ENSP00000479735
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005057 receptor signaling protein activity
GO:0005085 guanyl-nucleotide exchange factor activity
Biological Process
GO:0007165 signal transduction
GO:0007186 G-protein coupled receptor signaling pathway
GO:0007264 small GTPase mediated signal transduction
GO:0007399 nervous system development
GO:0035556 intracellular signal transduction
GO:0043547 positive regulation of GTPase activity
Cellular Component
GO:0005622 intracellular
GO:0016020 membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000038020
View Gene Order
ENSBTAG00000015232
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.632254 Hs.743875
RefSeq NM_016339 XM_006721932 XM_006721933 XM_006721934 XM_006721935 XM_006721936 XM_006721937 XM_006721938 XM_006721939
HUGO
OMIM
CCDS CCDS11363
HPRD 17954
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca