Version 5.4
Homo sapiens Gene: KRT40
Summary
InnateDB Gene IDBG-48476.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol KRT40
Gene Name keratin 40
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000204889
Encoded Proteins
IDBP-48478
keratin 40
IDBP-232971
keratin 40
IDBP-599249
keratin 40
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of the type I (acidic) keratin family, which belongs to the superfamily of intermediate filament (IF) proteins. Keratins are heteropolymeric structural proteins which form the intermediate filament. These filaments, along with actin microfilaments and microtubules, compose the cytoskeleton of epithelial cells. The type I keratin genes are clustered in a region of chromosome 17q12-q21. [provided by RefSeq, Jul 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 17:40977716-40987135
Strand Reverse strand
Band q21.2
Transcripts
ENST00000377755 ENSP00000366984
ENST00000398486 ENSP00000381500
ENST00000461923 ENSP00000434458
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.
Experimentally validated
Total 8 [view]
Protein-Protein 8 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005198 structural molecule activity
Biological Process
Cellular Component
GO:0005882 intermediate filament
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000059169
View Gene Order
ENSBTAG00000017408
Not yet available
Cross-References
SwissProt Q6A162
TrEMBL
UniProt Splice Variant
Entrez Gene 125115
UniGene Hs.534929
RefSeq NM_182497 XM_005257054 XM_005277788
HUGO HGNC:26707
OMIM
CCDS CCDS42320
HPRD 08304
IMGT
EMBL AJ786658 BC130396 BC150174 BC150191 BK004055
GenPept AAI30397 AAI50175 AAI50192 CAH10353 DAA04488
RNA Seq Atlas 125115

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca