Version 5.4
Homo sapiens Protein: KRT40
Summary
InnateDB Protein IDBP-48478.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol KRT40
Protein Name keratin 40
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000366984
InnateDB Gene IDBG-48476 (KRT40)
Protein Structure
UniProt Annotation
Function May play a role in late hair differentiation.
Subcellular Localization
Disease Associations
Tissue Specificity Expressed in skin and scalp. Also very weakly expressed in tongue, breast, colon and small intestine. In the hair follicle, it is specifically present in the upper hair cuticle. Not present in the upper cortex (at protein level). {ECO:0000269PubMed:15617563, ECO:0000269PubMed:17301834}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.
Experimentally validated
Total 8 [view]
Protein-Protein 8 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005198 structural molecule activity
Biological Process
Cellular Component
GO:0005882 intermediate filament
Protein Structure and Domains
PDB ID
InterPro IPR001664 Intermediate filament protein
IPR002957 Keratin, type I
PFAM PF00038
PRINTS PR01248
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q6A162
PhosphoSite PhosphoSite-Q6A162
TrEMBL
UniProt Splice Variant
Entrez Gene 125115
UniGene Hs.534929
RefSeq
HUGO HGNC:26707
OMIM
CCDS CCDS42320
HPRD 08304
IMGT
EMBL AJ786658 BC130396 BC150174 BC150191 BK004055
GenPept AAI30397 AAI50175 AAI50192 CAH10353 DAA04488

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca