Version 5.4
Homo sapiens Gene: TCF25
Summary
InnateDB Gene IDBG-48516.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TCF25
Gene Name transcription factor 25 (basic helix-loop-helix)
Synonyms hKIAA1049; Hulp1; NULP1; PRO2620
Species Homo sapiens
Ensembl Gene ENSG00000141002
Encoded Proteins
IDBP-48518
transcription factor 25 (basic helix-loop-helix)
IDBP-48522
transcription factor 25 (basic helix-loop-helix)
IDBP-745612
IDBP-747083
IDBP-745238
IDBP-747896
IDBP-751792
IDBP-752599
IDBP-749000
IDBP-746869
IDBP-750465
IDBP-806637
transcription factor 25 (basic helix-loop-helix)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary TCF25 is a member of the basic helix-loop-helix (bHLH) family of transcription factors that are important in embryonic development (Steen and Lindholm, 2008 [PubMed 18068114]).[supplied by OMIM, Sep 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 16:89873586-89911384
Strand Forward strand
Band q24.3
Transcripts
ENST00000263346 ENSP00000263346
ENST00000263347 ENSP00000263347
ENST00000564652 ENSP00000456080
ENST00000563636
ENST00000568412 ENSP00000457329
ENST00000564957
ENST00000562256 ENSP00000455611
ENST00000566751
ENST00000565196 ENSP00000454414
ENST00000565404 ENSP00000456592
ENST00000568870
ENST00000563484
ENST00000561958 ENSP00000456803
ENST00000566283 ENSP00000455471
ENST00000565860
ENST00000562193 ENSP00000456344
ENST00000570116
ENST00000568409 ENSP00000456840
ENST00000563032
ENST00000561585
ENST00000566158
ENST00000563406
ENST00000562184
ENST00000567171
ENST00000614813 ENSP00000484773
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 15 experimentally validated interaction(s) in this database.
Experimentally validated
Total 15 [view]
Protein-Protein 15 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0005515 protein binding
Biological Process
GO:0000122 negative regulation of transcription from RNA polymerase II promoter
GO:0006351 transcription, DNA-templated
GO:0007507 heart development
Cellular Component
GO:0005634 nucleus
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000001472
View Gene Order
ENSBTAG00000012102
Not yet available
Cross-References
SwissProt
TrEMBL H3BTU3
UniProt Splice Variant
Entrez Gene 22980
UniGene
RefSeq NM_014972 XM_005256298
HUGO HGNC:29181
OMIM 612326
CCDS CCDS10987
HPRD 13830
IMGT
EMBL AC092143 AC092385
GenPept
RNA Seq Atlas 22980

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca