Version 5.4
Homo sapiens Gene: PHLDA1
Summary
InnateDB Gene IDBG-48878.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PHLDA1
Gene Name pleckstrin homology-like domain, family A, member 1
Synonyms DT1P1B11; PHRIP; TDAG51
Species Homo sapiens
Ensembl Gene ENSG00000139289
Encoded Proteins
IDBP-48880
pleckstrin homology-like domain, family A, member 1
IDBP-810346
pleckstrin homology-like domain, family A, member 1
IDBP-810350
pleckstrin homology-like domain, family A, member 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes an evolutionarily conserved proline-histidine rich nuclear protein. The encoded protein may play an important role in the anti-apoptotic effects of insulin-like growth factor-1. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 12:76025447-76033932
Strand Reverse strand
Band q21.2
Transcripts
ENST00000266671 ENSP00000266671
ENST00000602540 ENSP00000473593
ENST00000619060 ENSP00000480767
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 15 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 15 [view]
Protein-Protein 13 [view]
Protein-DNA 1 [view]
Protein-RNA 1 [view]
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0006915 apoptotic process
GO:0021879 forebrain neuron differentiation
GO:0043065 positive regulation of apoptotic process
GO:0045210 FasL biosynthetic process
Cellular Component
GO:0005730 nucleolus
GO:0030659 cytoplasmic vesicle membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000020205
View Gene Order
ENSBTAG00000034985
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq NM_007350
HUGO
OMIM
CCDS CCDS31861
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca