Version 5.4
Mus musculus Gene: Hbxip
Summary
InnateDB Gene IDBG-489097.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Hbxip
Gene Name hepatitis B virus x interacting protein
Synonyms 1110003H18Rik; Hbxip; XIP
Species Mus musculus
Ensembl Gene ENSMUSG00000087260
Encoded Proteins
IDBP-627679
hepatitis B virus x interacting protein
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000134248:
This gene encodes a protein that specifically complexes with the C-terminus of hepatitis B virus X protein (HBx). The function of this protein is to negatively regulate HBx activity and thus to alter the replication life cycle of the virus. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 3:107278858-107284079
Strand Forward strand
Band F2.3
Transcripts
ENSMUST00000145735 ENSMUSP00000129012
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.
They are also associated with 57 interaction(s) predicted by orthology.
Experimentally validated
Total 8 [view]
Protein-Protein 8 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 57 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005085 guanyl-nucleotide exchange factor activity
GO:0005515 protein binding
GO:0032947 protein complex scaffold
Biological Process
GO:0008361 regulation of cell size
GO:0019079 viral genome replication
GO:0032008 positive regulation of TOR signaling
GO:0043066 negative regulation of apoptotic process
GO:0043087 regulation of GTPase activity
GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0043547 positive regulation of GTPase activity
GO:0061462 protein localization to lysosome
GO:0071230 cellular response to amino acid stimulus
Cellular Component
GO:0005764 lysosome
GO:0005829 cytosol
GO:0071986 Ragulator complex
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000134248
View Gene Order
ENSBTAG00000014970
Not yet available
Pathway Predictions based on Human Orthology Data
NETPATH
NetPath_2
AndrogenReceptor pathway
REACTOME
KEGG
INOH
PID NCI
Cross-References
SwissProt Q9D1L9
TrEMBL G3UW70
UniProt Splice Variant
Entrez Gene 68576
UniGene Mm.426872
RefSeq NM_026774
OMIM
CCDS CCDS51042
HPRD
IMGT
MGI ID MGI:1915826
MGI Symbol Lamtor5
EMBL AC132405 AK003358 AK146289 BC028547 CH466607
GenPept AAH28547 BAB22734 BAE27046 EDL01899
RNA Seq Atlas 68576

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca