Version 5.4
Homo sapiens Gene: PLEKHH2
Summary
InnateDB Gene IDBG-48929.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PLEKHH2
Gene Name pleckstrin homology domain containing, family H (with MyTH4 domain) member 2
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000152527
Encoded Proteins
IDBP-48933
pleckstrin homology domain containing, family H (with MyTH4 domain) member 2
IDBP-478078
pleckstrin homology domain containing, family H (with MyTH4 domain) member 2
IDBP-481877
pleckstrin homology domain containing, family H (with MyTH4 domain) member 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 2:43637273-43767987
Strand Forward strand
Band p21
Transcripts
ENST00000282406 ENSP00000282406
ENST00000405223
ENST00000405000
ENST00000491692 ENSP00000427746
ENST00000460356
ENST00000480103
ENST00000493408
ENST00000490038 ENSP00000430377
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003779 actin binding
GO:0005515 protein binding
GO:0042802 identical protein binding
Biological Process
GO:0030835 negative regulation of actin filament depolymerization
Cellular Component
GO:0005737 cytoplasm
GO:0005856 cytoskeleton
GO:0005886 plasma membrane
GO:0030027 lamellipodium
GO:0030864 cortical actin cytoskeleton
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000040852
View Gene Order
ENSBTAG00000032521
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.164162 Hs.605655 Hs.619243
RefSeq NM_172069 XM_006711941
HUGO
OMIM
CCDS CCDS1812
HPRD 15149
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca