Version 5.4
Homo sapiens Gene: GAS8
Summary
InnateDB Gene IDBG-48962.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol GAS8
Gene Name growth arrest-specific 8
Synonyms GAS11
Species Homo sapiens
Ensembl Gene ENSG00000141013
Encoded Proteins
IDBP-48966
growth arrest-specific 8
IDBP-599656
growth arrest-specific 8
IDBP-748036
IDBP-749028
IDBP-751481
IDBP-750379
IDBP-747042
IDBP-811171
growth arrest-specific 8
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene includes 11 exons spanning 25 kb and maps to a region of chromosome 16 that is sometimes deleted in breast and prostrate cancer. The second intron contains an apparently intronless gene, C16orf3, that is transcribed in the opposite orientation. This gene is a putative tumor suppressor gene. [provided by RefSeq, Jul 2008]
This gene includes 11 exons spanning 25 kb and maps to a region of chromosome 16 that is sometimes deleted in breast and prostrate cancer. The second intron contains an apparently intronless gene, C16orf3, that is transcribed in the opposite orientation. This gene is a putative tumor suppressor gene. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2013]
Gene Information
Type Protein coding
Genomic Location Chromosome 16:90019629-90044975
Strand Forward strand
Band q24.3
Transcripts
ENST00000268699 ENSP00000268699
ENST00000540721
ENST00000537797
ENST00000536122 ENSP00000440977
ENST00000568664
ENST00000564853
ENST00000561675 ENSP00000457554
ENST00000565000
ENST00000565062 ENSP00000455936
ENST00000564802
ENST00000566266 ENSP00000454343
ENST00000563936 ENSP00000454905
ENST00000564789
ENST00000569558
ENST00000568284
ENST00000563980
ENST00000565957
ENST00000568705
ENST00000564392 ENSP00000455172
ENST00000569399
ENST00000620723 ENSP00000482877
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0017137 Rab GTPase binding
Biological Process
GO:0008285 negative regulation of cell proliferation
GO:0030317 sperm motility
GO:0034613 cellular protein localization
Cellular Component
GO:0005794 Golgi apparatus
GO:0005874 microtubule
GO:0031514 motile cilium
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000040220
View Gene Order
ENSBTAG00000007096
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.431792 Hs.739124
RefSeq NM_001286205 NM_001286208 NM_001286209 NM_001481 XM_005256304 XM_005256309 XM_006721175
HUGO
OMIM
CCDS CCDS10992 CCDS67101 CCDS73932
HPRD 05533
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca